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Reactive oxygen generated by Nox1 triggers the angiogenic switch

The reactive oxygen-generating enzyme Nox1 transforms NIH 3T3 cells, rendering them highly tumorigenic and, as shown herein, also increases tumorigenicity of DU-145 prostate epithelial cells. Although Nox1 modestly stimulates cell division in both fibroblasts and epithelial cells, an increased mitog...

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Detalhes bibliográficos
Main Authors: Arbiser, Jack L., Petros, John, Klafter, Robert, Govindajaran, Baskaran, McLaughlin, Elizabeth R., Brown, Lawrence F., Cohen, Cynthia, Moses, Marsha, Kilroy, Susan, Arnold, Rebecca S., Lambeth, J. David
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC117371/
https://ncbi.nlm.nih.gov/pubmed/11805326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.022630199
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