Bufalin-loaded bovine serum albumin nanoparticles demonstrated improved anti-tumor activity against hepatocellular carcinoma: preparation, characterization, pharmacokinetics and tissue distribution

OBJECTIVE: To prepare and evaluate the liver-targeted drug delivery system of Bufalin with higher liver uptake and stronger antitumor activity against hepatocellular carcinoma. METHODS: Bufalin-loaded bovine serum albumin nanoparticle was prepared by desolvation method, to investigate the in vitro r...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Huiqing, Huang, Nian, Yang, Geliang, Lin, Qing, Su, Yonghua
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609923/
https://ncbi.nlm.nih.gov/pubmed/28968991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18800
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