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Stress inhibits tryptophan hydroxylase expression in a rat model of depression

Serotonin (5-hydroxytryptamine, 5-HT) dysfunction is associated with the pathophysiology of depression. Tryptophan hydroxylase (TPH), the rate-limiting enzyme in 5-HT biosynthesis, is believed to have essential role in many mental disorders, including depression. In the present study, we generated a...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Chen, Yi, Xu, Haixia, Zhu, Mingyue, Liu, Kun, Lin, Bo, Luo, Ruxian, Chen, Chuanbai, Li, Mengsen
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609917/
https://ncbi.nlm.nih.gov/pubmed/28968985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18780
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