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Tryptophan Hydroxylase-2: An Emerging Therapeutic Target for Stress Disorders

Serotonin (5-HT) has been long recognized to modulate the stress response, and dysfunction of 5-HT has been implicated in numerous stress disorders. Accordingly, the 5-HT system has been targeted for the treatment of stress disorders. Tryptophan hydroxylase (TPH) is the rate-limiting enzyme in 5-HT...

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Detalhes bibliográficos
Main Authors: Chen, Guo-Lin, Miller, Gregory M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727219/
https://ncbi.nlm.nih.gov/pubmed/23435356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2013.02.018
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