The distinct clinical features of giant cell tumor of bone in pagetic and non-pagetic patients are associated with genetic, biochemical and histological differences

Giant Cell Tumor of Bone (GCT) is a tumor characterized by neoplastic mesenchymal stromal cells and a high number of osteoclast-like multinucleated giant cells. Rarely, GCT could arise in bones affected by Paget's disease of bone (GCT/PDB). Although it is already known that GCT/PDB and GCT show...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Divisato, Giuseppina, di Carlo, Federica Scotto, Pazzaglia, Laura, Rizzo, Riccardo, Coviello, Domenico A., Benassi, Maria Serena, Picci, Piero, Esposito, Teresa, Gianfrancesco, Fernando
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609908/
https://ncbi.nlm.nih.gov/pubmed/28968976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18670
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