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Critical role of β1 integrin in postnatal beta-cell function and expansion

β1 integrin is essential for pancreatic beta-cell development and maintenance in rodents and humans. However, the effects of a temporal beta-cell specific β1 integrin knockout on adult islet function are unknown. We utilized a mouse insulin 1 promoter driven tamoxifen-inducible Cre-recombinase β1 in...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Peart, Jason, Li, Jinming, Lee, Hojun, Riopel, Matthew, Feng, Zhi-Chao, Wang, Rennian
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609893/
https://ncbi.nlm.nih.gov/pubmed/28968961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17969
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