Biscarbamate Cross-Linked Low-Molecular-Weight Polyethylenimine for Delivering Anti-chordin siRNA into Human Mesenchymal Stem Cells for Improving Bone Regeneration

Small-interfering RNA (siRNA) provides a rapid solution for drug design and provides new methods to develop customizable medicines. Polyethyleneimine 25 kDa (PEI25kDa) is an effective transfection agent used in siRNA delivery. However, the lack of degradable linkage causes undesirable toxicity, hind...

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Bibliografische gegevens
Gepubliceerd in:Front Pharmacol
Hoofdauteurs: Wang, Chuandong, Yuan, Weien, Xiao, Fei, Gan, Yaokai, Zhao, Xiaotian, Zhai, Zhanjing, Zhao, Xiaoying, Zhao, Chen, Cui, Penglei, Jin, Tuo, Chen, Xiaodong, Zhang, Xiaoling
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2017
Onderwerpen:
Pharmacology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609535/
https://ncbi.nlm.nih.gov/pubmed/28970797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00572
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