Biscarbamate Cross-Linked Low-Molecular-Weight Polyethylenimine for Delivering Anti-chordin siRNA into Human Mesenchymal Stem Cells for Improving Bone Regeneration

Small-interfering RNA (siRNA) provides a rapid solution for drug design and provides new methods to develop customizable medicines. Polyethyleneimine 25 kDa (PEI25kDa) is an effective transfection agent used in siRNA delivery. However, the lack of degradable linkage causes undesirable toxicity, hind...

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Dettagli Bibliografici
Pubblicato in:Front Pharmacol
Autori principali: Wang, Chuandong, Yuan, Weien, Xiao, Fei, Gan, Yaokai, Zhao, Xiaotian, Zhai, Zhanjing, Zhao, Xiaoying, Zhao, Chen, Cui, Penglei, Jin, Tuo, Chen, Xiaodong, Zhang, Xiaoling
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609535/
https://ncbi.nlm.nih.gov/pubmed/28970797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00572
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