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A simple and traceless solid phase method simplifies the assembly of large peptides and the access to challenging proteins

Chemical protein synthesis gives access to well-defined native or modified proteins that are useful for studying protein structure and function. The majority of proteins synthesized up to now have been produced using native chemical ligation (NCL) in solution. Although there are significant advantag...

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Библиографические подробности
Опубликовано в: :Chem Sci
Главные авторы: Ollivier, N., Desmet, R., Drobecq, H., Blanpain, A., Boll, E., Leclercq, B., Mougel, A., Vicogne, J., Melnyk, O.
Формат: Artigo
Язык:Inglês
Опубликовано: Royal Society of Chemistry 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609153/
https://ncbi.nlm.nih.gov/pubmed/28970915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc01912b
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