Bioenergetic state regulates innate inflammatory responses through the transcriptional co-repressor CtBP

The innate inflammatory response contributes to secondary injury in brain trauma and other disorders. Metabolic factors such as caloric restriction, ketogenic diet, and hyperglycemia influence the inflammatory response, but how this occurs is unclear. Here, we show that glucose metabolism regulates...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Shen, Yiguo, Kapfhamer, David, Minnella, Angela M., Kim, Ji-Eun, Won, Seok Joon, Chen, Yanting, Huang, Yong, Low, Ley Hian, Massa, Stephen M., Swanson, Raymond A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608947/
https://ncbi.nlm.nih.gov/pubmed/28935892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00707-0
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