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Lysine demethylase KDM2A inhibits TET2 to promote DNA methylation and silencing of tumor suppressor genes in breast cancer

The coupling between DNA methylation and histone modification contributes to aberrant expression of oncogenes or tumor suppressor genes that leads to tumor development. Our previous study demonstrated that lysine demethylase 2A (KDM2A) functions as an oncogene in breast cancer by promoting cancer st...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncogenesis
Päätekijät: Chen, J-Y, Luo, C-W, Lai, Y-S, Wu, C-C, Hung, W-C
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608919/
https://ncbi.nlm.nih.gov/pubmed/28785073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2017.71
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