Antibacterial and immunomodulatory activities of insect defensins-DLP2 and DLP4 against multidrug-resistant Staphylococcus aureus

Methicillin-resistant Staphylococcus aureus (MRSA), are the most frequent cause of sepsis, which urgently demanding new drugs for treating infection. Two homologous insect CSαβ peptides-DLP2 and DLP4 from Hermetia illucens were firstly expressed in Pichia pastoris, with the yields of 873.5 and 801.3...

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Udgivet i:Sci Rep
Main Authors: Li, Zhanzhan, Mao, Ruoyu, Teng, Da, Hao, Ya, Chen, Huixian, Wang, Xiumin, Wang, Xiao, Yang, Na, Wang, Jianhua
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608901/
https://ncbi.nlm.nih.gov/pubmed/28935900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10839-4
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