Endothelial Nox4-based NADPH oxidase regulates atherosclerosis via soluble epoxide hydrolase

Nox4-based NADPH oxidase is a major reactive oxygen species-generating enzyme in the vasculature, but its role in atherosclerosis remains controversial. OBJECTIVE: Our goal was to investigate the mechanisms of endothelial Nox4 in regulating atherosclerosis. APPROACH AND RESULTS: Atherosclerosis-pron...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biochim Biophys Acta
Prif Awduron: Hu, Pingping, Wu, Xiaojuan, Khandelwal, Alok R., Yu, Weimin, Xu, Zaicheng, Chen, Lili, Yang, Jian, Weisbrod, Robert M., Lee, Kin Sing Stephen, Seta, Francesca, Hammock, Bruce D., Cohen, Richard A., Zeng, Chunyu, Tong, Xiaoyong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608514/
https://ncbi.nlm.nih.gov/pubmed/28185955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2017.02.004
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