A comprehensive analysis of coregulator recruitment, androgen receptor function and gene expression in prostate cancer

Standard treatment for metastatic prostate cancer (CaP) prevents ligand-activation of androgen receptor (AR). Despite initial remission, CaP progresses while relying on AR. AR transcriptional output controls CaP behavior and is an alternative therapeutic target, but its molecular regulation is poorl...

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Publicat a:eLife
Autors principals: Liu, Song, Kumari, Sangeeta, Hu, Qiang, Senapati, Dhirodatta, Venkadakrishnan, Varadha Balaji, Wang, Dan, DePriest, Adam D, Schlanger, Simon E, Ben-Salem, Salma, Valenzuela, Malyn May, Willard, Belinda, Mudambi, Shaila, Swetzig, Wendy M, Das, Gokul M, Shourideh, Mojgan, Koochekpour, Shahriah, Falzarano, Sara Moscovita, Magi-Galluzzi, Cristina, Yadav, Neelu, Chen, Xiwei, Lao, Changshi, Wang, Jianmin, Billaud, Jean-Noel, Heemers, Hannelore V
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2017
Matèries:
Cancer Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608510/
https://ncbi.nlm.nih.gov/pubmed/28826481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28482
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