Protein Kinase N1 control of androgen-responsive Serum Response Factor action provides rationale for novel prostate cancer treatment strategy

Sustained reliance on androgen receptor (AR) after failure of AR-targeting androgen deprivation therapy (ADT) prevents effective treatment of castration-recurrent (CR) prostate cancer (CaP). Interfering with the molecular machinery by which AR drives CaP progression may be an alternative therapeutic...

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Pubblicato in:Oncogene
Autori principali: Venkadakrishnan, Varadha Balaji, DePriest, Adam D., Kumari, Sangeeta, Senapati, Dhirodatta, Ben-Salem, Salma, Su, Yixue, Mudduluru, Giridhar, Hu, Qiang, Cortes, Eduardo, Pop, Elena, Mohler, James L., Azabdaftari, Gissou, Attwood, Kristopher, Shah, Rajal B., Jamieson, Christina, Dehm, Scott M., Magi-Galluzzi, Cristina, Klein, Eric, Sharifi, Nima, Liu, Song, Heemers, Hannelore V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771259/
https://ncbi.nlm.nih.gov/pubmed/30742064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-019-0732-7
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