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Generation of Genetically Modified Mice through the Microinjection of Oocytes
The use of genetically modified mice has significantly contributed to studies on both physiological and pathological in vivo processes. The pronuclear injection of DNA expression constructs into fertilized oocytes remains the most commonly used technique to generate transgenic mice for overexpressio...
Guardat en:
| Publicat a: | J Vis Exp |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MyJove Corporation
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5608437/ https://ncbi.nlm.nih.gov/pubmed/28654070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55765 |
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