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Formyl peptide derived lipopeptides disclose differences between the receptors in mouse and men and call the pepducin concept in question
A pepducin is a lipopeptide containing a peptide sequence that is identical to one of the intracellular domains of the G-protein coupled receptor (GPCR) assumed to be the target. Neutrophils express two closely related formyl peptide receptors belonging to the family of GPCRs; FPR1 and FPR2 in human...
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| 發表在: | PLoS One |
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| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5608352/ https://ncbi.nlm.nih.gov/pubmed/28934373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185132 |
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