Stage specific requirement of platelet-derived growth factor receptor-α in embryonic development

BACKGROUND: Platelet-derived growth factor receptor alpha (PDGFRα) is a cell-surface receptor tyrosine kinase for platelet-derived growth factors. Correct timing and level of Pdgfra expression is crucial for embryo development, and deletion of Pdgfra caused developmental defects of multiple endoderm...

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Veröffentlicht in:PLoS One
Hauptverfasser: Qian, Chen, Wong, Carol Wing Yan, Wu, Zhongluan, He, Qiuming, Xia, Huimin, Tam, Paul Kwong Hang, Wong, Kenneth Kak Yuen, Lui, Vincent Chi Hang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608218/
https://ncbi.nlm.nih.gov/pubmed/28934221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184473
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