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Tpl2 Promotes Innate Cell Recruitment and Effector T Cell Differentiation To Limit Citrobacter rodentium Burden and Dissemination

Tumor progression locus 2 (Tpl2) is a serine-threonine kinase that regulates Th1 differentiation, secretion of the inflammatory cytokine gamma interferon (IFN-γ), and host defense against the intracellular pathogens Toxoplasma gondii, Listeria monocytogenes, and Mycobacterium tuberculosis. However,...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Main Authors: Acuff, Nicole V., Li, Xin, Latha, Krishna, Nagy, Tamas, Watford, Wendy T.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607429/
https://ncbi.nlm.nih.gov/pubmed/28760932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00193-17
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