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CD4(+)-T-Cell Effector Functions and Costimulatory Requirements Essential for Surviving Mucosal Infection with Citrobacter rodentium

Citrobacter rodentium causes an attaching and effacing infection of the mouse colon. Surprisingly, protective adaptive immunity against this mucosal pathogen requires a systemic T-cell-dependent antibody response. To define CD4(+) T-cell effector functions promoting this systemic defense of infected...

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Detalhes bibliográficos
Main Authors: Bry, Lynn, Brigl, Manfred, Brenner, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346620/
https://ncbi.nlm.nih.gov/pubmed/16369024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.1.673-681.2006
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