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Next-Generation Probiotics Targeting Clostridium difficile through Precursor-Directed Antimicrobial Biosynthesis

Integration of antibiotic and probiotic therapy has the potential to lessen the public health burden of antimicrobial-associated diseases. Clostridium difficile infection (CDI) represents an important example where the rational design of next-generation probiotics is being actively pursued to preven...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Main Authors: Spinler, Jennifer K., Auchtung, Jennifer, Brown, Aaron, Boonma, Prapaporn, Oezguen, Numan, Ross, Caná L., Luna, Ruth Ann, Runge, Jessica, Versalovic, James, Peniche, Alex, Dann, Sara M., Britton, Robert A., Haag, Anthony, Savidge, Tor C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607411/
https://ncbi.nlm.nih.gov/pubmed/28760934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00303-17
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