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Predicting ligand-dependent tumors from multi-dimensional signaling features
Targeted therapies have shown significant patient benefit in about 5–10% of solid tumors that are addicted to a single oncogene. Here, we explore the idea of ligand addiction as a driver of tumor growth. High ligand levels in tumors have been shown to be associated with impaired patient survival, bu...
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| Veröffentlicht in: | NPJ Syst Biol Appl |
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| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5607260/ https://ncbi.nlm.nih.gov/pubmed/28944080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41540-017-0030-3 |
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