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Organ-specific regulation of ATP7A abundance is coordinated with systemic copper homeostasis
Copper (Cu) is an essential cofactor for various enzymatic activities including mitochondrial electron transport, iron mobilization, and peptide hormone maturation. Consequently, Cu dysregulation is associated with fatal neonatal disease, liver and cardiac dysfunction, and anemia. While the Cu trans...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5607234/ https://ncbi.nlm.nih.gov/pubmed/28931909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11961-z |
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