The C5a/C5aR1 axis controls the development of experimental allergic asthma independent of LysM-expressing pulmonary immune cells

C5a regulates the development of maladaptive immune responses in allergic asthma mainly through the activation of C5a receptor 1 (C5aR1). Yet, the cell types and the mechanisms underlying this regulation are ill-defined. Recently, we described increased C5aR1 expression in lung tissue eosinophils bu...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Wiese, Anna V., Ender, Fanny, Quell, Katharina M., Antoniou, Konstantina, Vollbrandt, Tillman, König, Peter, Köhl, Jörg, Laumonnier, Yves
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607179/
https://ncbi.nlm.nih.gov/pubmed/28931049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184956
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