Načítá se...

Targeting βCys93 in hemoglobin S with an antisickling agent possessing dual allosteric and antioxidant effects

Sickle cell disease (SCD) is an inherited blood disorder caused by a β globin gene mutation of hemoglobin (HbS). The polymerization of deoxyHbS and its subsequent aggregation (into long fibers) is the primary molecular event which leads to red blood cell (RBC) sickling and ultimately hemolytic anemi...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Metallomics
Hlavní autoři: Kassa, Tigist, Strader, Michael Brad, Nakagawa, Akito, Zapol, Warren M., Alayash, Abdu I.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607114/
https://ncbi.nlm.nih.gov/pubmed/28770911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7mt00104e
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!