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A pH Switch for β-Sheet Folding
Protein design advancements have led to biotechnological strategies based on more stable and more specific structures. Herein we present a 6-residue sequence (HPATGK) that acts as a stable structure-nucleating turn at physiological and higher pH but is notably unfavorable for chain direction reversa...
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| Gepubliceerd in: | Angew Chem Int Ed Engl |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5607017/ https://ncbi.nlm.nih.gov/pubmed/28523654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201700860 |
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