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Amino‐acid composition after loop deletion drives domain swapping

Rational engineering of a protein to enable domain swapping requires an understanding of the sequence, structural and energetic factors that favor the domain‐swapped oligomer over the monomer. While it is known that the deletion of loops between β‐strands can promote domain swapping, the spliced seq...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Nandwani, Neha, Surana, Parag, Udgaonkar, Jayant B., Das, Ranabir, Gosavi, Shachi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5606538/
https://ncbi.nlm.nih.gov/pubmed/28710790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3237
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