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Amino‐acid composition after loop deletion drives domain swapping

Rational engineering of a protein to enable domain swapping requires an understanding of the sequence, structural and energetic factors that favor the domain‐swapped oligomer over the monomer. While it is known that the deletion of loops between β‐strands can promote domain swapping, the spliced seq...

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Bibliografiske detaljer
Udgivet i:Protein Sci
Main Authors: Nandwani, Neha, Surana, Parag, Udgaonkar, Jayant B., Das, Ranabir, Gosavi, Shachi
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5606538/
https://ncbi.nlm.nih.gov/pubmed/28710790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3237
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