Role of Nrf2 Signaling in the Regulation of Vascular BK Channel β1 Subunit Expression and BK Channel Function in High-Fat Diet–Induced Diabetic Mice

The large conductance Ca(2+)-activated K(+) (BK) channel β1-subunit (BK-β1) is a key modulator of BK channel electrophysiology and the downregulation of BK-β1 protein expression in vascular smooth muscle cells (SMCs) underlies diabetic vascular dysfunction. In this study, we hypothesized that the nu...

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Foilsithe in:Diabetes
Main Authors: Lu, Tong, Sun, Xiaojing, Li, Yong, Chai, Qiang, Wang, Xiao-Li, Lee, Hon-Chi
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Diabetes Association 2017
Ábhair:
Complications
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5606315/
https://ncbi.nlm.nih.gov/pubmed/28465407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db17-0181
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