Alteration of Inflammatory Mediators in the Upper and Lower Airways under Chronic Intermittent Hypoxia: Preliminary Animal Study

PURPOSE: We hypothesized that CIH may affect the upper airway immune system and aimed to verify whether CIH can induce airway inflammation in a murine obstructive sleep apnea (OSA) model. METHODS: C57BL6 male mice were exposed to intermittent hypoxia (CIH group; 5 ~ 21% FiO(2), 120 sec cycles, 12 h/...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Lee, Eun Jung, Heo, Woon, Kim, Joo Young, Kim, Hyungchul, Kang, Min Jung, Kim, Bo Ra, Kim, Ji Hyun, Park, Do Yang, Kim, Chang-Hoon, Yoon, Joo-Heon, Cho, Hyung-Ju
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5606044/
https://ncbi.nlm.nih.gov/pubmed/29038619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/4327237
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