Role of ADP receptors on platelets in the growth of ovarian cancer

We investigated the effect of platelets on ovarian cancer and the role of adenosine diphosphate (ADP) receptors (P2Y12 and P2Y1) on platelets in the growth of primary ovarian cancer tumors. We showed that in murine models of ovarian cancer, a P2Y12 inhibitor (ticagrelor) reduced tumor growth by 60%...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Cho, Min Soon, Noh, Kyunghee, Haemmerle, Monika, Li, Dan, Park, Hyun, Hu, Qianghua, Hisamatsu, Takeshi, Mitamura, Takashi, Mak, Sze Ling Celia, Kunapuli, Satya, Ma, Qing, Sood, Anil K., Afshar-Kharghan, Vahid
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
Assuntos:
Platelets and Thrombopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5606004/
https://ncbi.nlm.nih.gov/pubmed/28679740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-02-769893
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