Recurrent alterations of the WW domain containing oxidoreductase gene spanning the common fragile site FRA16D in multiple myeloma and monoclonal gammopathy of undetermined significance

The putative tumor suppressor gene WW domain containing oxidoreductase (WWOX) spans a common fragile site (CFS) on chromosome 16q23.3. CFSs are regions of profound genomic instability and sites for genomic deletions in cancer cells. Therefore, WWOX is structurally altered in diverse nonhematological...

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Pubblicato in:Oncol Lett
Autori principali: Handa, Hiroshi, Sasaki, Yoshiko, Hattori, Hikaru, Alkebsi, Lobna, Kasamatsu, Tetsuhiro, Saitoh, Takayuki, Mitsui, Takeki, Yokohama, Akihiko, Tsukamoto, Norifumi, Matsumoto, Morio, Murakami, Hirokazu
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2017
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605961/
https://ncbi.nlm.nih.gov/pubmed/28943951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6672
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