The cytokine polymorphisms affecting Th1/Th2 increase the susceptibility to, and severity of, chronic ITP

BACKGROUND: T-helper cell type 1 (Th1) polarization in chronic immune thrombocytopenia (cITP) has been reported at the protein and mRNA levels. We evaluated the impact of Th1/Th2 cytokine and cytokine receptor functional polymorphisms on both susceptibility to, and severity of, cITP. We analysed IFN...

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Veröffentlicht in:BMC Immunol
Hauptverfasser: Takahashi, Noriyuki, Saitoh, Takayuki, Gotoh, Nanami, Nitta, Yasuhiro, Alkebsi, Lobna, Kasamatsu, Tetsuhiro, Minato, Yusuke, Yokohama, Akihiko, Tsukamoto, Norifumi, Handa, Hiroshi, Murakami, Hirokazu
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434613/
https://ncbi.nlm.nih.gov/pubmed/28511637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-017-0210-3
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