Toxicity evaluation of methoxy poly(ethylene oxide)-block-poly(ε-caprolactone) polymeric micelles following multiple oral and intraperitoneal administration to rats

Methoxy poly(ethylene oxide)-block-poly(ɛ-caprolactone) (PEO-b-PCL) copolymers are amphiphilic and biodegradable copolymers designed to deliver a variety of drugs and diagnostic agents. The aim of this study was to synthesize PEO-b-PCL block copolymers and assess the toxic effects of drug-free PEO-b...

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Detalhes bibliográficos
Publicado no:Saudi Pharm J
Main Authors: Binkhathlan, Ziyad, Qamar, Wajhul, Ali, Raisuddin, Kfoury, Hala, Alghonaim, Mohammed
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605849/
https://ncbi.nlm.nih.gov/pubmed/28951683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2017.04.001
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