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Monitoring thioredoxin redox with a genetically encoded red fluorescent biosensor

Thioredoxin (Trx) is one of the two major thiol antioxidants playing essential roles in redox homeostasis and signaling. Despite the importance, there is a lack of method in monitoring Trx redox dynamics in live cells, hindering a better understanding of physiological and pathological roles of the T...

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Detalhes bibliográficos
Publicado no:Nat Chem Biol
Main Authors: Fan, Yichong, Makar, Merna, Wang, Michael X., Ai, Hui-wang
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605834/
https://ncbi.nlm.nih.gov/pubmed/28671680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2417
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