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The dynamic plasticity of insulin production in β-cells

BACKGROUND: Although the insulin-producing pancreatic β-cells are quite capable of adapting to both acute and chronic changes in metabolic demand, persistently high demand for insulin will ultimately lead to their progressive dysfunction and eventual loss. Recent and historical studies highlight the...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Boland, Brandon B., Rhodes, Christopher J., Grimsby, Joseph S.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605729/
https://ncbi.nlm.nih.gov/pubmed/28951821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.04.010
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