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Modifications and Trafficking of APP in the Pathogenesis of Alzheimer’s Disease
Alzheimer’s disease (AD), the most common neurodegenerative disorder, is the leading cause of dementia. Neuritic plaque, one of the major characteristics of AD neuropathology, mainly consists of amyloid β (Aβ) protein. Aβ is derived from amyloid precursor protein (APP) by sequential cleavages of β-...
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| Publicado no: | Front Mol Neurosci |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5605621/ https://ncbi.nlm.nih.gov/pubmed/28966576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00294 |
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