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Metals induce transient folding and activation of the Twister ribozyme
Twister is a small ribozyme present in almost all kingdoms of life that rapidly self-cleaves in variety of divalent metal ions. We used activity assays, bulk FRET and single-molecule FRET (smFRET) to understand how different metal ions promote folding and self-cleavage of the Oryza sativa Twister ri...
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| Опубликовано в: : | Nat Chem Biol |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5605428/ https://ncbi.nlm.nih.gov/pubmed/28825710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2459 |
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