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Bifurcation kinetics of drug uptake by Gram-negative bacteria

Cell envelopes of many bacteria consist of two membranes studded with efflux transporters. Such organization protects bacteria from the environment and gives rise to multidrug resistance. We report a kinetic model that accurately describes the permeation properties of this system. The model predicts...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Westfall, David A., Krishnamoorthy, Ganesh, Wolloscheck, David, Sarkar, Rupa, Zgurskaya, Helen I., Rybenkov, Valentin V.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604995/
https://ncbi.nlm.nih.gov/pubmed/28926596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184671
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