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Detection of Pentosidine Cross-Links in Cell-Secreted Decellularized Matrices Using Time Resolved Fluorescence Spectroscopy

Hyperglycemia-mediated, nonenzymatic collagen cross-links such as pentosidine (PENT) can have deleterious effects on cellular interactions with the extracellular matrix (ECM). Present techniques to quantify PENT are limited, motivating the need for improved methods to study the accumulation and cont...

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Detalhes bibliográficos
Publicado no:ACS Biomater Sci Eng
Main Authors: Mitra, Debika, Fatakdawala, Hussain, Nguyen-Truong, Michael, Creecy, Amy, Nyman, Jeffry, Marcu, Laura, Leach, J. Kent
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604893/
https://ncbi.nlm.nih.gov/pubmed/28944287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsbiomaterials.6b00029
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