Cell-secreted matrices perpetuate the bone-forming phenotype of differentiated mesenchymal stem cells

Prior to transplantation, mesenchymal stem/stromal cells (MSCs) can be induced toward the osteoblastic phenotype using a cocktail of soluble supplements. However, there is little evidence of differentiated MSCs directly participating in bone formation, suggesting that MSCs may either die or revert i...

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Udgivet i:Biomaterials
Main Authors: Hoch, Allison I., Mittal, Vaishali, Mitra, Debika, Vollmer, Nina, Zikry, Christopher A., Leach, J. Kent
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661076/
https://ncbi.nlm.nih.gov/pubmed/26457835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.10.003
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