A Randomized Controlled Trial of Lisinopril to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Individuals

BACKGROUND: In HIV infection, lymphoid tissue is disrupted by fibrosis. Angiotensin converting enzyme inhibitors have anti-fibrotic properties. We completed a pilot study to assess whether the addition of lisinopril to antiretroviral therapy (ART) reverses fibrosis of gut tissue, and whether this le...

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Detalhes bibliográficos
Publicado no:Pathog Immun
Main Authors: Cockerham, Leslie R., Yukl, Steven A., Harvill, Kara, Somsouk, Ma, Joshi, Sunil K., Sinclair, Elizabeth, Liegler, Teri, Hoh, Rebecca, Lyons, Sophie, Hunt, Peter W., Rupert, Adam, Sereti, Irini, Morcock, David R., Rhodes, Ajantha, Emson, Claire, Hellerstein, Marc K., Estes, Jacob D., Lewin, Sharon, Deeks, Steven G., Hatano, Hiroyu
Formato: Artigo
Idioma:Inglês
Publicado em: Pathogens and Immunity 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604865/
https://ncbi.nlm.nih.gov/pubmed/28936485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20411/pai.v2i3.207
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