Nardilysin is involved in autoimmune arthritis via the regulation of tumour necrosis factor alpha secretion

OBJECTIVE: Tumour necrosis factor alpha (TNF-α) plays an important role in rheumatoid arthritis (RA). TNF-α is synthesised as a membrane-anchored precursor and is fully activated by a disintegrin and metalloproteinase 17 (ADAM17)-mediated ectodomain shedding. Nardilysin (NRDC) facilitates ectodomain...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:RMD Open
Hauptverfasser: Fujii, Takayuki, Nishi, Eiichiro, Ito, Hiromu, Yoshitomi, Hiroyuki, Furu, Moritoshi, Okabe, Namiko, Ohno, Mikiko, Nishi, Kiyoto, Morita, Yusuke, Morita, Yugo, Azukizawa, Masayuki, Okahata, Akinori, Tomizawa, Takuya, Kimura, Takeshi, Matsuda, Shuichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: RMD Open 2017
Schlagworte:
Animal Models
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604610/
https://ncbi.nlm.nih.gov/pubmed/28955486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/rmdopen-2017-000436
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge