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The metal drives the chemistry: Dual functions of acireductone dioxygenase

Acireductone dioxygenase (ARD) from the methionine salvage pathway (MSP) is a unique enzyme that exhibits dual chemistry determined solely by the identity of the divalent transition metal ion (Fe(2+) or Ni(2+)) in the active site. The Fe(2+) containing isozyme catalyzes the on-pathway reaction using...

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Bibliografiske detaljer
Udgivet i:Chem Rev
Main Authors: Deshpande, Aditi R., Pochapsky, Thomas C., Ringe, Dagmar
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604235/
https://ncbi.nlm.nih.gov/pubmed/28731690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrev.7b00117
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