Acetylated Histones in Apoptotic Microparticles Drive the Formation of Neutrophil Extracellular Traps in Active Lupus Nephritis

OBJECTIVE: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the presence of autoantibodies against nuclear components. Lupus nephritis (LN) is the major cause of morbidity and mortality in patients with SLE. Central to the pathogenesis of SLE is the accumulation of cellul...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Rother, Nils, Pieterse, Elmar, Lubbers, Jelle, Hilbrands, Luuk, van der Vlag, Johan
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604071/
https://ncbi.nlm.nih.gov/pubmed/28959262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01136
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