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Acetylated Histones in Apoptotic Microparticles Drive the Formation of Neutrophil Extracellular Traps in Active Lupus Nephritis

OBJECTIVE: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the presence of autoantibodies against nuclear components. Lupus nephritis (LN) is the major cause of morbidity and mortality in patients with SLE. Central to the pathogenesis of SLE is the accumulation of cellul...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Rother, Nils, Pieterse, Elmar, Lubbers, Jelle, Hilbrands, Luuk, van der Vlag, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604071/
https://ncbi.nlm.nih.gov/pubmed/28959262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01136
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