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The Responses of Mouse Preimplantation Embryos to Leptin In Vitro in a Transgenerational Model for Obesity

The aim of the present study was to test the hypothesis that leptin can directly mediate the negative effect of maternal obesity on preimplantation embryos. As previously shown, maternal obesity retards early embryonic development in vivo and increases the incidence of apoptosis in blastocysts. When...

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Publicado en:Front Endocrinol (Lausanne)
Autores principales: Kšiňanová, Martina, Čikoš, Štefan, Babel’ová, Janka, Šefčíková, Zuzana, Špirková, Alexandra, Koppel, Juraj, Fabian, Dušan
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604062/
https://ncbi.nlm.nih.gov/pubmed/28959235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2017.00233
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