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The Responses of Mouse Preimplantation Embryos to Leptin In Vitro in a Transgenerational Model for Obesity

The aim of the present study was to test the hypothesis that leptin can directly mediate the negative effect of maternal obesity on preimplantation embryos. As previously shown, maternal obesity retards early embryonic development in vivo and increases the incidence of apoptosis in blastocysts. When...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Kšiňanová, Martina, Čikoš, Štefan, Babel’ová, Janka, Šefčíková, Zuzana, Špirková, Alexandra, Koppel, Juraj, Fabian, Dušan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604062/
https://ncbi.nlm.nih.gov/pubmed/28959235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2017.00233
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