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The Responses of Mouse Preimplantation Embryos to Leptin In Vitro in a Transgenerational Model for Obesity

The aim of the present study was to test the hypothesis that leptin can directly mediate the negative effect of maternal obesity on preimplantation embryos. As previously shown, maternal obesity retards early embryonic development in vivo and increases the incidence of apoptosis in blastocysts. When...

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Detaylı Bibliyografya
Yayımlandı:Front Endocrinol (Lausanne)
Asıl Yazarlar: Kšiňanová, Martina, Čikoš, Štefan, Babel’ová, Janka, Šefčíková, Zuzana, Špirková, Alexandra, Koppel, Juraj, Fabian, Dušan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604062/
https://ncbi.nlm.nih.gov/pubmed/28959235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2017.00233
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