Exploring regulation in tissues with eQTL networks

Characterizing the collective regulatory impact of genetic variants on complex phenotypes is a major challenge in developing a genotype to phenotype map. Using expression quantitative trait locus (eQTL) analyses, we constructed bipartite networks in which edges represent significant associations bet...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Fagny, Maud, Paulson, Joseph N., Kuijjer, Marieke L., Sonawane, Abhijeet R., Chen, Cho-Yi, Lopes-Ramos, Camila M., Glass, Kimberly, Quackenbush, John, Platig, John
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2017
Témata:
PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604022/
https://ncbi.nlm.nih.gov/pubmed/28851834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1707375114
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