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Enhanced degradation of misfolded proteins promotes tumorigenesis

An adequate cellular capacity to degrade misfolded proteins is critical for cell survival and organismal health. A diminished capacity is associated with aging and neurodegenerative diseases; however, the consequences of an enhanced capacity remain undefined. Here we report that the ability to clear...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Chen, Liang, Brewer, Michael D., Guo, Lili, Wang, Ruoxing, Jiang, Peng, Yang, Xiaolu
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603913/
https://ncbi.nlm.nih.gov/pubmed/28355566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.03.010
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