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Enhanced degradation of misfolded proteins promotes tumorigenesis
An adequate cellular capacity to degrade misfolded proteins is critical for cell survival and organismal health. A diminished capacity is associated with aging and neurodegenerative diseases; however, the consequences of an enhanced capacity remain undefined. Here we report that the ability to clear...
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出版年: | Cell Rep |
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主要な著者: | , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
2017
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5603913/ https://ncbi.nlm.nih.gov/pubmed/28355566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.03.010 |
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