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Cysteine Isocyanide in Multicomponent Reaction: Synthesis of Peptido-Mimetic 1,3-Azoles

[Image: see text] An alternative approach toward the simple and robust synthesis of highly substituted peptidic thiazole derivatives using Ugi-multicomponent reaction (U-MCR) is described. Thus, we introduced the enantiopure (R)-2-methyl-2-isocyano-3-(tritylthio)propanoate as a novel class of isocya...

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Publicat a:J Org Chem
Autors principals: Vishwanatha, Thimmalapura M., Kurpiewska, Katarzyna, Kalinowska-Tłuścik, Justyna, Dömling, Alexander
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2017
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603900/
https://ncbi.nlm.nih.gov/pubmed/28817272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.7b01615
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